Unless this is your first time to this blog (and if so, hi; take a look around and ignore the sarcasm long enough to realize I am actually a nice person), you know that I use a lot of pixels to chat about immunotherapy. What you may not know (I honestly didn’t), is that apparently there’s a classification for melanomas… Read more »
The immune system is an incredible evolutionary machine, designed to protect us from the ravages of bacteria, viruses, and other harmful microbes. But admittedly, there are some times when the immune system doesn’t work the way it is supposed to, giving rise to auto-immune disorders. And now scientists have demonstrated how a hijack of the immune system from melanoma cells… Read more »
Immunotherapy is helping cancer patients, including those with melanoma, to more successfully fight their diseases. However, a new study released in this month’sĀ Cancer Discovery highlights the fact that a more personalized approach could be even more successful. Brief background… immunotherapy works by activating the body’s T cells to find and destroy cancer cells. Obviously, this only works if the T… Read more »
Immunotherapy has been featured a lot on this blog because of the potential to dramatically improve the survival rates of cancer patients, including those struck by melanoma. Obviously, I’m not the only one excited about the progress made in this field. This year’s Nobel Prize in medicine was awarded to two immunology researchers – Dr. James Allison of the MD… Read more »
When I wrote my previous blog post about checkpoint inhibitor immunotherapy, I didn’t realize that Phase 2 of the clinical trials were being released later on that day. Researchers at the University of Texas MD Anderson Cancer Center (here in the Lone Star State) performed clinical trial checkpoint inhibitor immunotherapy in 94 patients with melanoma that had spread to the… Read more »
So in the last post, I talked about checkpoint blockade immunotherapy and the results it had on prolonging survival rates for those with brain metastases. In the post, I referenced a protein called PD-1, which is found on T cells and acts as a brake on the immune response. Using immune checkpoint inhibitor drugs releases that brake and allows the… Read more »
As I have mentioned a few times in this blog, melanoma has a disconcerting tendency to spread to the lungs, liver, and brain when it enters into the metastasizing stages. And brain tumors like that are pretty darn hard to treat. Most of the current treatments don’t really provide much benefit to patients. And once melanoma metastasizes, only about half… Read more »
If you follow the news regarding advancements in melanoma detection and treatment as much as I do, you may have seen the news story that researchers in Australia have been working on developing a blood test that could identify early-stage melanoma. This is really exciting news because as we all know, the earlier you detect melanoma, the better the odds… Read more »
I’m back in Austin – for a few days at least. I got in late last night and am not looking forward to the mounds of laundry I need to do before Monday night. Hawaii was beautiful. My cousin and her family were lots of fun to be around and the entire week was pretty laid back. Despite my fears… Read more »
Science is really cool… and a new research study from the team at theĀ Perelman School of Medicine at the University of Pennsylvania (an Ivy League school, BTW) thinks it may have the answer on why women with a history of a previous pregnancy statistically end up with better outcomes after a melanoma diagnosis. I’m going to quote a passage on… Read more »